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• Penichet, Manuel L. - Cancer and IgE: introducing the concept of allergooncology.

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Contenido

The first volume based on the field named 'AllergoOncology' The term 'AllergoOncology', recently created by Dr. Jensen-Jarolim, aims to reveal the function of IgE-mediated immune responses against tumor cells in order to enhance the understanding of its biology and develop novel treatment options based on IgE against malignant diseases

   INDICE: Introduction.- The biology of IgE: molecular mechanism restrainingpotentially dangerous high serum IgE titres in vivo.-The biology of IgE: the generation of high affinity IgE antibodies.- Epidemiological evidence: IgE, atopy and aolid tumors.- Epidemiological evidence: IgE, allergies, and hematopoietic malignancies.- Mast cells in allergy and tumor disease.- The IgE antibody and its use in cancer immunotherapy.- IgE interacts with potent effector cells against tumors: ADCC and ADCP.- IgE as adjuvant in tumor vaccination.- The targets of IgE: allergen-associated and tumor-associated molecular patterns (AAMPs and TAMPs).- The role of Th2-mediated anti-tumor immunity in tumor surveillance and clearance.

Detalles del artículo

• Páginas : 210
• Editorial : Humana
• Idioma : Inglés
• Fecha de Publicación : 01/12/2009
• ISBN: 9781607614500
• Encuadernación : Cartoné
• Nº Volúmenes : 1
• País de Publicación : Reino Unido (INGLATERRA)