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Contenido

This comprehensive textbook offers a globally-relevant account of the properties of all types of antimicrobial agent that are used in human medicine and provides authoritative guidance on the principles and practice of antimicrobial chemotherapy. The increasing problem of multi-drug resistance and the wide range of new antiviral therapies now available for the treatment of HIV and other viral infections are two of the new areas discussed in this comprehensive eighth edition. In addition to full coverage of every commonly used antibiotic agent, there are extensive chapters on all antiviral, antiprotozoan and anthelminthic agents.Completely revised throughout, with contributions from over 60 experts in infections disease/ medical microbiology worldwide, this edition reviews antimicrobial agents and the new antifungal therapies (voriconazole, liposomal amphotericin B) in detail, and covers pharmacokinetic sections in a more clinically relevant, less theoretical manner. There are specific tables on major drug interactions, placental transfer and concentrations of agents in breast milk, and new sections on liver failure, drug development and licensing, and the implications of xenotransplantation. The quinolone chapter has been greatly expanded to cover the wider spectrum of activity of the newer agents, and more information has been added on the new antimalarial combination therapies. The text includes cross-referencing to key web-sites (for example, the CDC website) to direct the reader to the source of the most up-to-date information on treatment, drug resistance and more.

   INDICE: Part I General aspects: Historical Introduction; Modes of Action; Resistance; Pharmacokinetics; Antibiotics in Renal Failure; Drug Interactions Involving Antimicrobial Agents; Toxicity; Antibiotics and the Immune System; General Principles of Chemotherapy; Laboratory Control of Antimicrobial Therapy; Principles of Chemoprophylaxis; Antibiotic Policies. Part II Agents: Aminoglycosides and Aminocyclitols; b-lactams - Cephalosporins; b-lactams - Penicillins; Other b-lactams; Chloramphenicol and Thiamphenicol; Coumarins; Cyclic Peptides; Cycloserine, Amino Acid Analogues and Oligopeptides; Diaminopyrimidines; Fosfomycin and Fosmidomycin; Fusidanes; Glycopeptides; Hexamine; Lincosamides; Macrolides; Mupirocin; Nitrofurans; Nitroimidazoles; Streptogramins; Quinolones; Rifamycins; Sulphonamides; Tetracyclines; Antifungal Agents; Antimycobacterial Agents; Anthelmintics; Antiprotozoal Agents; Antiviral Agents. Part III Treatment: Septicaemia; Abdominal and Other Surgical Infections; Infections Associated with Neutropenia and Transplants; Infections in Intensive Care Patients; Infections Associated with Implanted Devices; HIV and AIDS; Infections of the Upper Respiratory Tract; Infections of the Lower Respiratory Tract; Endocarditis; Infections of the Gastro-Intestinal Tract; Hepatitis; Infections of the Skin and Soft Tissues; Infections of the Central Nervous System; Bone and Joint Infections; Infections of the Eye; Urinary Tract Infections; Infections in Obstetrics; Sexually Transmitted Infections; Mycobacterial Infection; Fungal Infections; Zoonoses; Malaria; Other Protozoal Infections; Helminthic Infections.

Detalles del artículo

• Páginas : 1000
• Editorial : Churchill Livingstone
• Idioma : Inglés
• Fecha de Publicación : 01/03/2003
• ISBN: 9780443071294
• Encuadernación : Cartoné
• Nº Volúmenes : 1
• Nº Edición : 8
• País de Publicación : Reino Unido (INGLATERRA)