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Contenido

Antibiotic resistance is the ability of a micro-organism to withstand the effects of antibiotics. There are three mechanisms that can cause antibiotic resistance: prevention of interaction of drug with target, decreased uptake due to either an increased efflux or a decreased influx of the antimicrobial agent and enzymatic modification or destruction of the compound. In the past couple years, antibiotic resistance has become an increasing public health concern. Tuberculosis, gonorrhea, malaria and childhood ear infections are just a few of the diseases that have become hard to treat with antibiotic drugs. This book addresses the concern that over the past few years, there has been a major rise in resistance to antibiotics among gram-negative bacteria. New antibacterial drugs with novel modes of actions are urgently required in order to fight against infection. Novel antibiotics such as linezolid, carbapenem ertapenem, daptomycin and gemifloxacin are examined in this book. The genetic approaches used in risk assessment of antibiotic resistance dissemination are looked at as well. Furthermore, this book discusses the present studies on the use of veterinary antibiotics in agriculture, on the occurrence of antibiotic compounds and resistant bacteria in soil and water and clearly demonstrates the need for further studies

   INDICE: Preface; The phenomenon of antibiotic resistance in an evolutionary perspective; Antibiotic Resistance And Probiotics: Roles, Mechanisms And Evidence; When good bugs fight bad -- designing probiotics to control antibiotic resistant ‘superbugs’; Modification of the bacterial phenotype as an approach to counter the emergence of multidrug-resistant pathogens; Performance to antibiotics in staphylococcus aureus, streptococcus agalactiae and enterococcus spp; Microbiological And Pharmacological Principles Of Recent Antibiotic Therapy; Application of computational methods to study antibiotic resistance mechanisms. Fluoroquinolone resistance as a case study; Energetics of MDR microbial cells; Low Impact of OmpC AND OmpF On Susceptibility To Antibiotics In Clinical Isolates Of Escherichia coli Producers Of Extended-Spectrum Beta-Lactamases; Antibiotic resistance in mariculture environments of China; Antibiotic Resistance as a Method for Determining Sources of Fecal Pollution in Water; Genetic regulation, physiology, assessment and inhibition of efflux pumps responsible for multi-drug resistant phenotypes of bacterial pathogens; Tracking down a new putative drug target for osteoporosis: Structure of an essential region of the proton translocation channel of H+-VO-ATPase; Antibiotic Resistance In Food Lactic Acid Bacteria; Current status of antibiotic resistance in lactic acid bacteria; Microbiology, University of Stellenbosch, South Africa, and others); Veterinary Antibiotics And Their Possible Impact On Resistant Bacteria In The Environment; Index.

Detalles del artículo

• Páginas : 527
• Editorial : Nova Science
• Idioma : Inglés
• Fecha de Publicación : 25/03/2010
• ISBN: 9781607416234
• Encuadernación : Cartoné
• Nº Volúmenes : 1
• País de Publicación : Estados Unidos