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The reader will be introduced to various aspects of the fundamentals of nanotechnology based drug delivery systems and the application of these systems for the delivery of small molecules, proteins, peptides, oligonucleotides and genes. How these systems overcome challenges offered by biological barriers to drug absorption and drug targeting will also be described. Designed as a reference text on the application of nanotechnology in the development of drug delivery systems.
INDICE: From the contents Section 1: Fundamentals of Nanotechnology in Drug Delivery.- Unique Physicochemical Properties of Nanotechnology in Drug Delivery.- PEG Syntheses for Nanotechnology in Drug and Gene Delivery.- Supercritical Fluid Technology for Nanotechnology in Drug Delivery.- Nanotubes, Nanorods, Nanofibers, and Fullerenes for Nanoscale Drug Delivery.- Drug Loading and In Vitro Release Properties of Nanotechnology.- Nanotechnology Based Biosensors in Drug Delivery.- Section 2: Biopharmaceutical, Physiological and Clinical Considerations for Nanotechnology in Drug Delivery.- Nanomaterials and Biocompatibility: Biomems and Dendrimers.- Nanomaterials and Biocompatibility: Carbon Nanotubes and Fullerenes.- Factors Controlling Pharmacokinetics of Intravenously Injected Nanoparticulate Systems.- Controlled Release of Nanotechnology.- Nanotechnology for Intracellular Delivery and Targeting.- Section 3: Nanotechnology for the Delivery of Small Molecules, Peptide, Protein and Nucleic Acids.
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